Urokinase 3D Structures
From Proteopedia
(Difference between revisions)
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{{#tree:id=OrganizedByTopic|openlevels=0| | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
| - | *Urokinase | + | *Urokinase' Domains - N terminal 21-163; Kringle 69-153; catalytic 179-431 |
| - | **[[2i9a]] - hUK Hc N terminal | + | **[[2i9a]] - hUK Hc N terminal - human<br /> |
**[[1urk]] - hUK Hc N terminal – NMR<br /> | **[[1urk]] - hUK Hc N terminal – NMR<br /> | ||
| - | **[[1kdu]] – hUK kringle domain | + | **[[1kdu]] – hUK kringle domain - NMR<br /> |
| - | **[[4dva]] – hUK catalytic domain | + | **[[4dva]] – hUK catalytic domain <br /> |
**[[4xsk]] - hUK catalytic domain (mutant) <br /> | **[[4xsk]] - hUK catalytic domain (mutant) <br /> | ||
**[[5lhs]] - UK catalytic domain (mutant) - mouse<br /> | **[[5lhs]] - UK catalytic domain (mutant) - mouse<br /> | ||
| - | *Urokinase catalytic domain | + | *Urokinase catalytic domain complex with inhibitors |
| - | **[[4fu7]], [[4fu8]], [[4fu9]], [[4fub]], [[5xg4]], [[5wxs]] - hUK + inhibitor<br /> | + | **[[1c5w]], [[1c5x]], [[1c5y]], [[1c5z]], [[1lmw]], [[3ig6]], [[4fu7]], [[4fu8]], [[4fu9]], [[4fub]], [[5xg4]], [[5wxs]] - hUK + inhibitor<br /> |
| - | **[[1f92]], [[1sc8]], [[1vj9]], [[1vja]], [[2o8t]], [[2o8u]], [[2o8w]], [[4h42]], [[4mnv]],[[5wxt]] - hUK (mutant) + inhibitor<br /> | + | **[[1f92]], [[1gi7]], [[1gi8]], [[1gi9]], [[1gj7]], [[1gj8]], [[1gj9]], [[1gja]], [[1gjb]], [[1gjc]], [[1gjd]], [[1o3p]], [[1o5a]], [[1o5b]], [[1o5c]], [[1sc8]], [[1vj9]], [[1vja]], [[2o8t]], [[2o8u]], [[2o8w]], [[3kgp]], [[3khv]], [[3kid]], [[3mhw]], [[3mwi]], [[3ox7]], [[3oy5]], [[3oy6]], [[4h42]], [[4mnv]],[[5wxt]] - hUK (mutant) + inhibitor<br /> |
**[[1fv9]] – hUK (mutant) + benzimidazole derivative <br /> | **[[1fv9]] – hUK (mutant) + benzimidazole derivative <br /> | ||
**[[5yc6]], [[5yc7]] - hUK (mutant) + benzylamine derivative<br /> | **[[5yc6]], [[5yc7]] - hUK (mutant) + benzylamine derivative<br /> | ||
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**[[2vin]], [[2vio]], [[2vip]], [[2viq]], [[2viv]], [[2viw]] - hUK (mutant) + mexiletine derivative<br /> | **[[2vin]], [[2vio]], [[2vip]], [[2viq]], [[2viv]], [[2viw]] - hUK (mutant) + mexiletine derivative<br /> | ||
**[[3qn7]], [[4jk5]], [[4jk6]], [[4x1n]], [[4x1q]], [[4x1r]], [[4x1s]], [[4x0w]], [[4x1p]], [[4zhl]], [[4zhm]], [[4zkn]], [[4zko]], [[4zkr]], [[4zks]] - hUK (mutant) + peptide inhibitor<br /> | **[[3qn7]], [[4jk5]], [[4jk6]], [[4x1n]], [[4x1q]], [[4x1r]], [[4x1s]], [[4x0w]], [[4x1p]], [[4zhl]], [[4zhm]], [[4zkn]], [[4zko]], [[4zkr]], [[4zks]] - hUK (mutant) + peptide inhibitor<br /> | ||
| - | **[[4mnw]], [[4mnx]], [[4mny]], [[4os1]], [[4os2]], [[4os4]], [[4os5]], [[4os6]], [[4os7]] - hUK (mutant) + bicyclic peptide <br /> | + | **[[2nwn]], [[3m61]], [[4gly]], [[4mnw]], [[4mnx]], [[4mny]], [[4os1]], [[4os2]], [[4os4]], [[4os5]], [[4os6]], [[4os7]] - hUK (mutant) + bicyclic peptide <br /> |
**[[2vnt]], [[2r2w]] - hUK + guanidine derivative<br /> | **[[2vnt]], [[2r2w]] - hUK + guanidine derivative<br /> | ||
**[[5xg4]] - hUK + quercetin<br /> | **[[5xg4]] - hUK + quercetin<br /> | ||
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**[[5wxp]]- hUK + UPAIN-2-3-W3F<br /> | **[[5wxp]]- hUK + UPAIN-2-3-W3F<br /> | ||
**[[5wxr]]- hUK + UPAIN-2-4-W3F<br /> | **[[5wxr]]- hUK + UPAIN-2-4-W3F<br /> | ||
| - | |||
| - | *Urokinase C terminal complex with inhibitors | ||
| - | |||
| - | **[[3kgp]] – hUK Hc C terminal (mutant) + benzoic acid derivative<br /> | ||
| - | **[[3khv]] - hUK Hc C terminal (mutant) + methanol derivative<br /> | ||
| - | **[[3mwi]] - hUK Hc C terminal (mutant) + amidine derivative<br /> | ||
| - | **[[3ox7]], [[3oy5]], [[3oy6]] - hUK Hc C terminal (mutant) + peptide inhibitor<br /> | ||
| - | **[[3kid]], [[3mhw]] - hUK Hc C terminal (mutant) + aminobenzothiazole derivative<br /> | ||
| - | **[[2nwn]], [[4gly]] - hUK Hc C terminal + cyclic peptide<br /> | ||
| - | **[[3m61]] - hUK Hc C terminal (mutant) + cyclic peptide | ||
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| - | *Urokinase short chain + catalytic domain complex with inhibitors | ||
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| - | **[[1lmw]] – hUK A+B catalytic domain + EGRCMK<br /> | ||
| - | **[[1c5w]], [[1c5x]], [[1c5y]], [[1c5z]] - hUK A+B chain catalytic domain + carboxamidine derivative<br /> | ||
| - | **[[1gi7]], [[1gi8]], [[1gi9]], [[1gj7]], [[1gj8]], [[1gj9]], [[1gja]], [[1gjb]], [[1gjc]], [[1gjd]] - hUK A+B chain catalytic domain (mutant) + carboxamidine derivative<br /> | ||
| - | **[[1o3p]], [[1o5a]], [[1o5b]], [[1o5c]] - hUK A+B chain catalytic domain (mutant) + benzenolate derivative<br /> | ||
| - | **[[3ig6]] – hUK A+B chain catalytic domain + inhibitor<br /> | ||
*Urokinase complex with protein | *Urokinase complex with protein | ||
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**[[3laq]], [[3u73]] - hUK Hc N terminal + UK receptor<br /> | **[[3laq]], [[3u73]] - hUK Hc N terminal + UK receptor<br /> | ||
**[[2i9b]] - hUK Hc N terminal + UK receptor (mutant)<br /> | **[[2i9b]] - hUK Hc N terminal + UK receptor (mutant)<br /> | ||
| - | **[[3pb1]] - hUK Hc | + | **[[3pb1]] - hUK Hc catalytic domain (mutant) + UK inhibitor<br /> |
**[[4dw2]] - hUK B chain catalytic domain + antibody<br /> | **[[4dw2]] - hUK B chain catalytic domain + antibody<br /> | ||
**[[5hgg]] - hUK catalytic domain (mutant) + antibody<br /> | **[[5hgg]] - hUK catalytic domain (mutant) + antibody<br /> | ||
Revision as of 08:50, 9 January 2021
3D Structures of urokinase
Updated on 09-January-2021 - For a general description of the protein see Urokinase
