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6tgv
From Proteopedia
(Difference between revisions)
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<StructureSection load='6tgv' size='340' side='right'caption='[[6tgv]], [[Resolution|resolution]] 2.50Å' scene=''> | <StructureSection load='6tgv' size='340' side='right'caption='[[6tgv]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6tgv]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[6tgv]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TGV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6TGV FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CTP:CYTIDINE-5-TRIPHOSPHATE'>CTP</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CTP:CYTIDINE-5-TRIPHOSPHATE'>CTP</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">coaBC, MSMEG_3054, MSMEI_2978 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6tgv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tgv OCA], [https://pdbe.org/6tgv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6tgv RCSB], [https://www.ebi.ac.uk/pdbsum/6tgv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6tgv ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/COABC_MYCS2 COABC_MYCS2]] Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.[HAMAP-Rule:MF_02225] | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Current revision
Crystal structure of Mycobacterium smegmatis CoaBC in complex with CTP and FMN
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Categories: Large Structures | Myctu | Blaszczyk, M | Blundell, T L | Bryant, O | Cory-Wright, J | Mendes, V | Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate-cysteine ligase | Coabc | Ligase | Phosphopantothenate-cysteine ligase | Phosphopantothenoylcysteine decarboxylase | Phosphopantothenoylcysteine synthetase
