This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1dk4

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1dk4.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1dk4.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1dk4| PDB=1dk4 | SCENE= }}
{{STRUCTURE_1dk4| PDB=1dk4 | SCENE= }}
-
'''CRYSTAL STRUCTURE OF MJ0109 GENE PRODUCT INOSITOL MONOPHOSPHATASE'''
+
===CRYSTAL STRUCTURE OF MJ0109 GENE PRODUCT INOSITOL MONOPHOSPHATASE===
-
==Overview==
+
<!--
-
In sequenced genomes, protein coding regions with unassigned function constitute between 10 and 50% of all open reading frames. Often key enzymes cannot be identified using sequence homology searches. For example, despite the fact that methanogens have an apparently functional gluconeogenesis pathway, standard tools have been unable to identify a fructose-1,6-bisphosphatase (FBPase) gene in the sequenced Methanoccocus jannaschii genome. Using a combination of functional and structural tools, we have shown that the protein product of the M. jannaschii gene MJ0109, which had been tentatively annotated as an inositol monophosphatase (IMPase), has both IMPase and FBPase activities. Moreover, several gene products annotated as IMPases from different thermophilic organisms also possess FBPase activity. Thus, we have found the FBPase that was 'missing' in thermophiles and shown that it also functions as an IMPase.
+
The line below this paragraph, {{ABSTRACT_PUBMED_11062561}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 11062561 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_11062561}}
==About this Structure==
==About this Structure==
Line 30: Line 34:
[[Category: Complexed with zn and pi]]
[[Category: Complexed with zn and pi]]
[[Category: Homodimer]]
[[Category: Homodimer]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 13:56:29 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 23:11:24 2008''

Revision as of 20:11, 30 June 2008

Image:1dk4.png

Template:STRUCTURE 1dk4

CRYSTAL STRUCTURE OF MJ0109 GENE PRODUCT INOSITOL MONOPHOSPHATASE

Template:ABSTRACT PUBMED 11062561

About this Structure

1DK4 is a Single protein structure of sequence from Methanocaldococcus jannaschii. Full crystallographic information is available from OCA.

Reference

MJ0109 is an enzyme that is both an inositol monophosphatase and the 'missing' archaeal fructose-1,6-bisphosphatase., Stec B, Yang H, Johnson KA, Chen L, Roberts MF, Nat Struct Biol. 2000 Nov;7(11):1046-50. PMID:11062561

Page seeded by OCA on Mon Jun 30 23:11:24 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1dk4"
Personal tools