2a4v
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='2a4v' size='340' side='right'caption='[[2a4v]], [[Resolution|resolution]] 1.80Å' scene=''> | <StructureSection load='2a4v' size='340' side='right'caption='[[2a4v]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2a4v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2a4v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A4V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A4V FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> |
| - | + | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a4v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a4v OCA], [https://pdbe.org/2a4v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a4v RCSB], [https://www.ebi.ac.uk/pdbsum/2a4v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a4v ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a4v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a4v OCA], [https://pdbe.org/2a4v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a4v RCSB], [https://www.ebi.ac.uk/pdbsum/2a4v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a4v ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/DOT5_YEAST DOT5_YEAST] Has a role in telomere silencing, which is the repression of chromatin structure which leads to a stop in the transcription of nearby genes. Also has a role in the regulation of telomere length. Acts as an alkyl-hydroperoxide reductase in the nucleus during post-diauxic growth. Preferentially reduces alkyl-hydroperoxides rather than hydrogen preoxide. Acts as an antioxidant necessary for stationary phase survival.<ref>PMID:9755194</ref> <ref>PMID:12730197</ref> <ref>PMID:12925864</ref> | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 27: | Line 26: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Atcc 18824]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Saccharomyces cerevisiae]] |
| - | [[Category: Cha | + | [[Category: Cha M-K]] |
| - | [[Category: Choi | + | [[Category: Choi J]] |
| - | [[Category: Choi | + | [[Category: Choi S]] |
| - | [[Category: Chon | + | [[Category: Chon J-K]] |
| - | [[Category: Kim | + | [[Category: Kim I-H]] |
| - | [[Category: Shin | + | [[Category: Shin W]] |
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Crystal Structure of a truncated mutant of yeast nuclear thiol peroxidase
| |||||||||||
Categories: Large Structures | Saccharomyces cerevisiae | Cha M-K | Choi J | Choi S | Chon J-K | Kim I-H | Shin W
