2ajp

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Current revision (07:25, 23 August 2023) (edit) (undo)
 
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<StructureSection load='2ajp' size='340' side='right'caption='[[2ajp]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='2ajp' size='340' side='right'caption='[[2ajp]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2ajp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AJP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AJP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2ajp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AJP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AJP FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PDXK, PKH, PNK ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Pyridoxal_kinase Pyridoxal kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.35 2.7.1.35] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ajp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ajp OCA], [https://pdbe.org/2ajp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ajp RCSB], [https://www.ebi.ac.uk/pdbsum/2ajp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ajp ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ajp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ajp OCA], [https://pdbe.org/2ajp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ajp RCSB], [https://www.ebi.ac.uk/pdbsum/2ajp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ajp ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/PDXK_HUMAN PDXK_HUMAN]] Required for synthesis of pyridoxal-5-phosphate from vitamin B6.
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[https://www.uniprot.org/uniprot/PDXK_HUMAN PDXK_HUMAN] Required for synthesis of pyridoxal-5-phosphate from vitamin B6.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Pyridoxal kinase]]
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[[Category: Arrowsmith C]]
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[[Category: Arrowsmith, C]]
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[[Category: Atanassova A]]
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[[Category: Atanassova, A]]
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[[Category: Bochkarev A]]
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[[Category: Bochkarev, A]]
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[[Category: Dimov S]]
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[[Category: Dimov, S]]
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[[Category: Edwards A]]
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[[Category: Edwards, A]]
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[[Category: Ismail S]]
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[[Category: Ismail, S]]
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[[Category: Park H]]
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[[Category: Park, H]]
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[[Category: Sundstrom M]]
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[[Category: Structural genomic]]
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[[Category: Tempel W]]
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[[Category: Sundstrom, M]]
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[[Category: Weigelt J]]
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[[Category: Tempel, W]]
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[[Category: Weigelt, J]]
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[[Category: Sgc]]
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[[Category: Transferase]]
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Current revision

Crystal structure of a human pyridoxal kinase

PDB ID 2ajp

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