6y6o
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | ==Structure of mature activin A with small molecule | + | ==Structure of mature activin A with small molecule 42== |
| - | <StructureSection load='6y6o' size='340' side='right'caption='[[6y6o]]' scene=''> | + | <StructureSection load='6y6o' size='340' side='right'caption='[[6y6o]], [[Resolution|resolution]] 2.04Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Y6O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6Y6O FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6y6o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Y6O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6Y6O FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6y6o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6y6o OCA], [https://pdbe.org/6y6o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6y6o RCSB], [https://www.ebi.ac.uk/pdbsum/6y6o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6y6o ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.04Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OCK:(3~{R})-4-ethyl-3-methyl-3-propyl-1~{H}-1,4-benzodiazepine-2,5-dione'>OCK</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6y6o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6y6o OCA], [https://pdbe.org/6y6o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6y6o RCSB], [https://www.ebi.ac.uk/pdbsum/6y6o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6y6o ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/INHBA_HUMAN INHBA_HUMAN] Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Activin|Activin]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Brear PB]] | [[Category: Brear PB]] | ||
Revision as of 13:20, 24 January 2024
Structure of mature activin A with small molecule 42
| |||||||||||
