7jue
From Proteopedia
(Difference between revisions)
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==C-type carbohydrate-recognition domain 4 of the mannose receptor complexed with Man-alpha1-2Man== | ==C-type carbohydrate-recognition domain 4 of the mannose receptor complexed with Man-alpha1-2Man== | ||
| - | <StructureSection load='7jue' size='340' side='right'caption='[[7jue]]' scene=''> | + | <StructureSection load='7jue' size='340' side='right'caption='[[7jue]], [[Resolution|resolution]] 1.40Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7JUE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7JUE FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7jue]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7JUE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7JUE FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7jue FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7jue OCA], [https://pdbe.org/7jue PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7jue RCSB], [https://www.ebi.ac.uk/pdbsum/7jue PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7jue ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7jue FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7jue OCA], [https://pdbe.org/7jue PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7jue RCSB], [https://www.ebi.ac.uk/pdbsum/7jue PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7jue ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MRC1_HUMAN MRC1_HUMAN] Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria, fungi and other pathogens. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Feinberg H]] | [[Category: Feinberg H]] | ||
[[Category: Weis WI]] | [[Category: Weis WI]] | ||
Revision as of 07:16, 3 April 2024
C-type carbohydrate-recognition domain 4 of the mannose receptor complexed with Man-alpha1-2Man
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