This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2cyx

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:21, 25 October 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='2cyx' size='340' side='right'caption='[[2cyx]], [[Resolution|resolution]] 2.56&Aring;' scene=''>
<StructureSection load='2cyx' size='340' side='right'caption='[[2cyx]], [[Resolution|resolution]] 2.56&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2cyx]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CYX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CYX FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2cyx]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CYX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CYX FirstGlance]. <br>
-
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">UBE2G2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.56&#8491;</td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Ubiquitin--protein_ligase Ubiquitin--protein ligase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.19 6.3.2.19] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cyx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cyx OCA], [https://pdbe.org/2cyx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cyx RCSB], [https://www.ebi.ac.uk/pdbsum/2cyx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cyx ProSAT], [https://www.topsan.org/Proteins/RSGI/2cyx TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cyx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cyx OCA], [https://pdbe.org/2cyx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cyx RCSB], [https://www.ebi.ac.uk/pdbsum/2cyx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cyx ProSAT], [https://www.topsan.org/Proteins/RSGI/2cyx TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[https://www.uniprot.org/uniprot/UB2G2_HUMAN UB2G2_HUMAN]] Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Involved in endoplasmic reticulum-associated degradation (ERAD).<ref>PMID:20061386</ref> <ref>PMID:22607976</ref>
+
[https://www.uniprot.org/uniprot/UB2G2_HUMAN UB2G2_HUMAN] Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Involved in endoplasmic reticulum-associated degradation (ERAD).<ref>PMID:20061386</ref> <ref>PMID:22607976</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 31: Line 30:
==See Also==
==See Also==
-
*[[Ubiquitin conjugating enzyme|Ubiquitin conjugating enzyme]]
+
*[[3D structures of ubiquitin conjugating enzyme|3D structures of ubiquitin conjugating enzyme]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Ubiquitin--protein ligase]]
+
[[Category: Arai R]]
-
[[Category: Arai, R]]
+
[[Category: Imai Y]]
-
[[Category: Imai, Y]]
+
[[Category: Murayama K]]
-
[[Category: Murayama, K]]
+
[[Category: Shirouzu M]]
-
[[Category: Structural genomic]]
+
[[Category: Takahashi R]]
-
[[Category: Shirouzu, M]]
+
[[Category: Yokoyama S]]
-
[[Category: Takahashi, R]]
+
[[Category: Yoshikawa S]]
-
[[Category: Yokoyama, S]]
+
-
[[Category: Yoshikawa, S]]
+
-
[[Category: Ligase]]
+
-
[[Category: National project on protein structural and functional analyse]]
+
-
[[Category: Nppsfa]]
+
-
[[Category: Rsgi]]
+
-
[[Category: Ubl conjugation pathway]]
+

Current revision

Structure of human ubiquitin-conjugating enzyme E2 G2 (UBE2G2/UBC7)

PDB ID 2cyx

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2cyx"
Personal tools