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2dn7
From Proteopedia
(Difference between revisions)
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==Solution structures of the 6th fn3 domain of human receptor-type tyrosine-protein phosphatase F== | ==Solution structures of the 6th fn3 domain of human receptor-type tyrosine-protein phosphatase F== | ||
| - | <StructureSection load='2dn7' size='340' side='right'caption='[[2dn7 | + | <StructureSection load='2dn7' size='340' side='right'caption='[[2dn7]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2dn7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2dn7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DN7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DN7 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dn7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dn7 OCA], [https://pdbe.org/2dn7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dn7 RCSB], [https://www.ebi.ac.uk/pdbsum/2dn7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dn7 ProSAT], [https://www.topsan.org/Proteins/RSGI/2dn7 TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dn7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dn7 OCA], [https://pdbe.org/2dn7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dn7 RCSB], [https://www.ebi.ac.uk/pdbsum/2dn7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dn7 ProSAT], [https://www.topsan.org/Proteins/RSGI/2dn7 TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/PTPRF_HUMAN PTPRF_HUMAN] Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase).<ref>PMID:10338209</ref> The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one.<ref>PMID:10338209</ref> | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | + | [[Category: Inoue M]] | |
| - | [[Category: Inoue | + | [[Category: Kigawa T]] |
| - | [[Category: Kigawa | + | [[Category: Koshiba S]] |
| - | [[Category: Koshiba | + | [[Category: Sato M]] |
| - | + | [[Category: Tochio N]] | |
| - | [[Category: Sato | + | [[Category: Yokoyama S]] |
| - | [[Category: Tochio | + | |
| - | [[Category: Yokoyama | + | |
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Current revision
Solution structures of the 6th fn3 domain of human receptor-type tyrosine-protein phosphatase F
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Categories: Homo sapiens | Large Structures | Inoue M | Kigawa T | Koshiba S | Sato M | Tochio N | Yokoyama S
