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2dt5

From Proteopedia

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Current revision (18:46, 29 May 2024) (edit) (undo)
 
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<StructureSection load='2dt5' size='340' side='right'caption='[[2dt5]], [[Resolution|resolution]] 2.16&Aring;' scene=''>
<StructureSection load='2dt5' size='340' side='right'caption='[[2dt5]], [[Resolution|resolution]] 2.16&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2dt5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DT5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DT5 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2dt5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DT5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DT5 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.16&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TTHA1657 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dt5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dt5 OCA], [https://pdbe.org/2dt5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dt5 RCSB], [https://www.ebi.ac.uk/pdbsum/2dt5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dt5 ProSAT], [https://www.topsan.org/Proteins/RSGI/2dt5 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dt5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dt5 OCA], [https://pdbe.org/2dt5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dt5 RCSB], [https://www.ebi.ac.uk/pdbsum/2dt5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dt5 ProSAT], [https://www.topsan.org/Proteins/RSGI/2dt5 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/REX_THET8 REX_THET8]] Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.[HAMAP-Rule:MF_01131]
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[https://www.uniprot.org/uniprot/REX_THET8 REX_THET8] Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.[HAMAP-Rule:MF_01131]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Thet8]]
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[[Category: Thermus thermophilus HB8]]
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[[Category: Kita, A]]
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[[Category: Kita A]]
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[[Category: Komori, H]]
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[[Category: Komori H]]
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[[Category: Miki, K]]
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[[Category: Miki K]]
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[[Category: Nakamura, A]]
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[[Category: Nakamura A]]
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[[Category: Structural genomic]]
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[[Category: Sosa A]]
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[[Category: Sosa, A]]
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[[Category: Dna binding protein]]
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[[Category: Nad]]
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[[Category: Nadh]]
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[[Category: Redox sensing]]
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[[Category: Rex]]
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[[Category: Rossmann fold]]
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[[Category: Rsgi]]
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[[Category: Thermus themophilus]]
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[[Category: Winged helix]]
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Current revision

Crystal Structure of TTHA1657 (AT-rich DNA-binding protein) from Thermus thermophilus HB8

PDB ID 2dt5

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