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2dxf
From Proteopedia
(Difference between revisions)
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<StructureSection load='2dxf' size='340' side='right'caption='[[2dxf]], [[Resolution|resolution]] 1.70Å' scene=''> | <StructureSection load='2dxf' size='340' side='right'caption='[[2dxf]], [[Resolution|resolution]] 1.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2dxf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2dxf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DXF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DXF FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene></td></tr> | |
| - | <tr id=' | + | |
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dxf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dxf OCA], [https://pdbe.org/2dxf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dxf RCSB], [https://www.ebi.ac.uk/pdbsum/2dxf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dxf ProSAT], [https://www.topsan.org/Proteins/RSGI/2dxf TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dxf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dxf OCA], [https://pdbe.org/2dxf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dxf RCSB], [https://www.ebi.ac.uk/pdbsum/2dxf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dxf ProSAT], [https://www.topsan.org/Proteins/RSGI/2dxf TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/NDK_PYRHO NDK_PYRHO] Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | + | [[Category: Pyrococcus horikoshii OT3]] | |
| - | [[Category: Pyrococcus horikoshii]] | + | [[Category: Kato-Murayama M]] |
| - | [[Category: Kato-Murayama | + | [[Category: Murayama K]] |
| - | [[Category: Murayama | + | [[Category: Shirouzu M]] |
| - | + | [[Category: Terada T]] | |
| - | [[Category: Shirouzu | + | [[Category: Yokoyama S]] |
| - | [[Category: Terada | + | |
| - | [[Category: Yokoyama | + | |
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Current revision
Crystal structure of nucleoside diphosphate kinase in complex with GTP analog
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