2e60
From Proteopedia
(Difference between revisions)
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==Solution structure of the surp1 domain in splicing factor, arginine/serine-rich 8== | ==Solution structure of the surp1 domain in splicing factor, arginine/serine-rich 8== | ||
| - | <StructureSection load='2e60' size='340' side='right'caption='[[2e60 | + | <StructureSection load='2e60' size='340' side='right'caption='[[2e60]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2e60]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2e60]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E60 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E60 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e60 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e60 OCA], [https://pdbe.org/2e60 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e60 RCSB], [https://www.ebi.ac.uk/pdbsum/2e60 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e60 ProSAT], [https://www.topsan.org/Proteins/RSGI/2e60 TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e60 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e60 OCA], [https://pdbe.org/2e60 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e60 RCSB], [https://www.ebi.ac.uk/pdbsum/2e60 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e60 ProSAT], [https://www.topsan.org/Proteins/RSGI/2e60 TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SFSWA_HUMAN SFSWA_HUMAN] Plays a role as an alternative splicing regulator. Regulate its own expression at the level of RNA processing. Also regulates the splicing of fibronectin and CD45 genes. May act, at least in part, by interaction with other R/S-containing splicing factors. Represses the splicing of MAPT/Tau exon 10.<ref>PMID:8940107</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2e60 ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2e60 ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: He | + | [[Category: He F]] |
| - | [[Category: Inoue | + | [[Category: Inoue M]] |
| - | [[Category: Kigawa | + | [[Category: Kigawa T]] |
| - | [[Category: Muto | + | [[Category: Muto Y]] |
| - | + | [[Category: Shirouzu M]] | |
| - | [[Category: Shirouzu | + | [[Category: Terada T]] |
| - | [[Category: Terada | + | [[Category: Yokoyama S]] |
| - | [[Category: Yokoyama | + | |
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Current revision
Solution structure of the surp1 domain in splicing factor, arginine/serine-rich 8
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Categories: Homo sapiens | Large Structures | He F | Inoue M | Kigawa T | Muto Y | Shirouzu M | Terada T | Yokoyama S
