2egw

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Current revision (13:49, 13 March 2024) (edit) (undo)
 
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<StructureSection load='2egw' size='340' side='right'caption='[[2egw]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='2egw' size='340' side='right'caption='[[2egw]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2egw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"aquifex_aeolicus"_huber_and_stetter_2001 "aquifex aeolicus" huber and stetter 2001]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EGW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EGW FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2egw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EGW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EGW FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2egv|2egv]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RsmE ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=63363 "Aquifex aeolicus" Huber and Stetter 2001])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2egw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2egw OCA], [https://pdbe.org/2egw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2egw RCSB], [https://www.ebi.ac.uk/pdbsum/2egw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2egw ProSAT], [https://www.topsan.org/Proteins/RSGI/2egw TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2egw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2egw OCA], [https://pdbe.org/2egw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2egw RCSB], [https://www.ebi.ac.uk/pdbsum/2egw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2egw ProSAT], [https://www.topsan.org/Proteins/RSGI/2egw TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/RSME_AQUAE RSME_AQUAE]] Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity).
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[https://www.uniprot.org/uniprot/RSME_AQUAE RSME_AQUAE] Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Aquifex aeolicus huber and stetter 2001]]
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[[Category: Aquifex aeolicus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Bessho, Y]]
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[[Category: Bessho Y]]
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[[Category: Dong, X]]
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[[Category: Dong X]]
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[[Category: Structural genomic]]
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[[Category: Shirouzu M]]
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[[Category: Shirouzu, M]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S]]
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[[Category: M3u]]
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[[Category: Methyltransferase]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Pua domain]]
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[[Category: Rna methyltransferase]]
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[[Category: Rrna modification]]
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[[Category: Rsgi]]
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[[Category: Rsme]]
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[[Category: Sah]]
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Current revision

Crystal structure of rRNA methyltransferase with SAH ligand

PDB ID 2egw

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