This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2ep8
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Solution structure of the BRCT domain from human Pescadillo homolog 1== | ==Solution structure of the BRCT domain from human Pescadillo homolog 1== | ||
| - | <StructureSection load='2ep8' size='340' side='right'caption='[[2ep8 | + | <StructureSection load='2ep8' size='340' side='right'caption='[[2ep8]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2ep8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2ep8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EP8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EP8 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ep8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ep8 OCA], [https://pdbe.org/2ep8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ep8 RCSB], [https://www.ebi.ac.uk/pdbsum/2ep8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ep8 ProSAT], [https://www.topsan.org/Proteins/RSGI/2ep8 TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ep8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ep8 OCA], [https://pdbe.org/2ep8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ep8 RCSB], [https://www.ebi.ac.uk/pdbsum/2ep8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ep8 ProSAT], [https://www.topsan.org/Proteins/RSGI/2ep8 TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/PESC_HUMAN PESC_HUMAN] Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.<ref>PMID:16738141</ref> <ref>PMID:17353269</ref> <ref>PMID:17189298</ref> | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 23: | Line 23: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Hayashi | + | [[Category: Hayashi F]] |
| - | [[Category: Nagashima | + | [[Category: Nagashima T]] |
| - | + | [[Category: Yokoyama S]] | |
| - | [[Category: Yokoyama | + | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Solution structure of the BRCT domain from human Pescadillo homolog 1
| |||||||||||
