This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2eqi
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Solution structure of the SH3 domain from Phospholipase C, gamma 2== | ==Solution structure of the SH3 domain from Phospholipase C, gamma 2== | ||
| - | <StructureSection load='2eqi' size='340' side='right'caption='[[2eqi | + | <StructureSection load='2eqi' size='340' side='right'caption='[[2eqi]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2eqi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2eqi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EQI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EQI FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eqi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eqi OCA], [https://pdbe.org/2eqi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eqi RCSB], [https://www.ebi.ac.uk/pdbsum/2eqi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eqi ProSAT], [https://www.topsan.org/Proteins/RSGI/2eqi TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eqi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eqi OCA], [https://pdbe.org/2eqi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eqi RCSB], [https://www.ebi.ac.uk/pdbsum/2eqi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eqi ProSAT], [https://www.topsan.org/Proteins/RSGI/2eqi TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/PLCG2_MOUSE PLCG2_MOUSE] The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling (By similarity). | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 25: | Line 25: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Mus musculus]] |
| - | [[Category: Hayahsi | + | [[Category: Hayahsi F]] |
| - | [[Category: Nagashima | + | [[Category: Nagashima T]] |
| - | [[Category: Qin | + | [[Category: Qin XR]] |
| - | + | [[Category: Yokoyama S]] | |
| - | [[Category: Yokoyama | + | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Solution structure of the SH3 domain from Phospholipase C, gamma 2
| |||||||||||
