1e9w
From Proteopedia
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1e9w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_azureus Streptomyces azureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E9W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1E9W FirstGlance]. <br> | <table><tr><td colspan='2'>[[1e9w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_azureus Streptomyces azureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E9W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1E9W FirstGlance]. <br> | ||
| - | </td></tr><tr id=' | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BB9:(2Z)-2-AMINO-3-SULFANYLPROP-2-ENOIC+ACID'>BB9</scene>, <scene name='pdbligand=DBU:(2Z)-2-AMINOBUT-2-ENOIC+ACID'>DBU</scene>, <scene name='pdbligand=DCY:D-CYSTEINE'>DCY</scene>, <scene name='pdbligand=DHA:2-AMINO-ACRYLIC+ACID'>DHA</scene>, <scene name='pdbligand=MH6:3-HYDROXY-2-IMINOPROPANOIC+ACID'>MH6</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=PRD_000223:THIOSTREPTON'>PRD_000223</scene>, <scene name='pdbligand=QUA:8-HYDROXY-4-(1-HYDROXYETHYL)QUINOLINE-2-CARBOXYLIC+ACID'>QUA</scene>, <scene name='pdbligand=TS9:(2S,3S,4R)-2-AMINO-3,4-DIHYDROXY-3-METHYLPENTANOIC+ACID'>TS9</scene></td></tr> |
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1e9w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e9w OCA], [https://pdbe.org/1e9w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1e9w RCSB], [https://www.ebi.ac.uk/pdbsum/1e9w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1e9w ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1e9w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e9w OCA], [https://pdbe.org/1e9w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1e9w RCSB], [https://www.ebi.ac.uk/pdbsum/1e9w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1e9w ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/THCL_STRAJ THCL_STRAJ] Has bacteriocidal activity. Inhibits bacterial protein biosynthesis by acting on the elongation factor Tu (EF-Tu) (By similarity). | |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Streptomyces azureus]] | [[Category: Streptomyces azureus]] | ||
| - | [[Category: Alphey | + | [[Category: Alphey MS]] |
| - | [[Category: Bond | + | [[Category: Bond CS]] |
| - | [[Category: Hunter | + | [[Category: Hunter WN]] |
| - | [[Category: Shaw | + | [[Category: Shaw MP]] |
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Revision as of 11:20, 30 November 2022
Structure of the macrocycle thiostrepton solved using the anomalous dispersive contribution from sulfur
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