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Sandbox GGC17
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The disease that Keratin 4 causes is white sponge nenus. White sponge nevus is an autosomal dominant disease which is caused by amutation of a certain keratin genes. White sponge nevus is going to be a main componenet for a group of inherited diseases that are going to provide a white bilateral, keratinized apperance typically appearing on the buccal mucosa. | The disease that Keratin 4 causes is white sponge nenus. White sponge nevus is an autosomal dominant disease which is caused by amutation of a certain keratin genes. White sponge nevus is going to be a main componenet for a group of inherited diseases that are going to provide a white bilateral, keratinized apperance typically appearing on the buccal mucosa. | ||
== Relevance == | == Relevance == | ||
| - | + | The two way parallel beta-sheet is where the C-terminal strand of one monomer is being positioned and anti-parallel to the N-terminal strand of the main adjacent monomer and this arrangement is not seen so far in any of the homologous structures. This is the <scene name='87/874949/00rainbow_ribbon/1'>Keratin 4 protein</scene>. | |
== Structural highlights == | == Structural highlights == | ||
| - | This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes | + | This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. This is the <scene name='87/874949/00helix1_res/1'>Alpha helix residues zoomed in</scene>. This is the <scene name='87/874949/00helix1_res/2'>Alpha helix residues zoomed out</scene> |
</StructureSection> | </StructureSection> | ||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 16:49, 26 April 2021
Keratin 4
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References
- ↑ doi: https://dx.doi.org/10.1016/j.ijbiomac.201412048
- ↑ Moore PS, Hierholzer J, DeWitt W, Gouan K, Djore D, Lippeveld T, Plikaytis B, Broome CV. Respiratory viruses and mycoplasma as cofactors for epidemic group A meningococcal meningitis. JAMA. 1990 Sep 12;264(10):1271-5. PMID:2117679
