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Sandbox GGC16
From Proteopedia
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==PU.1== | ==PU.1== | ||
<StructureSection load='1PUE' size='340' side='right' caption='Caption for this structure' scene=''> | <StructureSection load='1PUE' size='340' side='right' caption='Caption for this structure' scene=''> | ||
| - | PU.1 is a hematopoietic transcription factor. It specifically regulates transcription of macrophage and B cell genes in stem cells, ultimately leading to cellular differentiation | + | PU.1 is a hematopoietic transcription factor. It specifically regulates transcription of macrophage and B cell genes in stem cells, ultimately leading to cellular differentiation. |
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | ||
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| + | == Name == | ||
| + | The name PU.1 comes from the protein's binding interactions with a purine-rich DNA sequence. | ||
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== Function == | == Function == | ||
Revision as of 20:11, 24 February 2021
PU.1
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References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
