Sandbox GGC16

PU.1 is a hematopoietic transcription factor. It specifically regulates transcription of macrophage and B cell genes in stem cells, ultimately leading to cellular differentiation.

Name

The name PU.1 comes from the protein's binding interactions with a purine-rich DNA sequence.

Function

Binding Domain

Disease

Relevance

Structural highlights

This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.