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6xuj

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Current revision (13:12, 24 January 2024) (edit) (undo)
 
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==HumRadA1 in complex with 5-Ethyl-N-(1H-indol-5-ylmethyl)-1,3,4-thiadiazol-2-amine in P21212==
==HumRadA1 in complex with 5-Ethyl-N-(1H-indol-5-ylmethyl)-1,3,4-thiadiazol-2-amine in P21212==
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<StructureSection load='6xuj' size='340' side='right'caption='[[6xuj]]' scene=''>
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<StructureSection load='6xuj' size='340' side='right'caption='[[6xuj]], [[Resolution|resolution]] 1.54&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6XUJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6XUJ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6xuj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus_DSM_3638 Pyrococcus furiosus DSM 3638]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6XUJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6XUJ FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6xuj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6xuj OCA], [https://pdbe.org/6xuj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6xuj RCSB], [https://www.ebi.ac.uk/pdbsum/6xuj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6xuj ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.54&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=O1E:5-Ethyl-N-(1H-indol-5-ylmethyl)-1,3,4-thiadiazol-2-amine'>O1E</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6xuj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6xuj OCA], [https://pdbe.org/6xuj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6xuj RCSB], [https://www.ebi.ac.uk/pdbsum/6xuj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6xuj ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RADA_PYRFU RADA_PYRFU] Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Pyrococcus furiosus DSM 3638]]
[[Category: Hyvonen M]]
[[Category: Hyvonen M]]
[[Category: Marsh ME]]
[[Category: Marsh ME]]
[[Category: Scott DE]]
[[Category: Scott DE]]

Current revision

HumRadA1 in complex with 5-Ethyl-N-(1H-indol-5-ylmethyl)-1,3,4-thiadiazol-2-amine in P21212

PDB ID 6xuj

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