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6w10

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Current revision (14:14, 18 October 2023) (edit) (undo)
 
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<StructureSection load='6w10' size='340' side='right'caption='[[6w10]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='6w10' size='340' side='right'caption='[[6w10]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6w10]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6W10 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6W10 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6w10]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6W10 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6W10 FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Trex1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8000338&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Exodeoxyribonuclease_III Exodeoxyribonuclease III], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.11.2 3.1.11.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6w10 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6w10 OCA], [https://pdbe.org/6w10 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6w10 RCSB], [https://www.ebi.ac.uk/pdbsum/6w10 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6w10 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6w10 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6w10 OCA], [https://pdbe.org/6w10 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6w10 RCSB], [https://www.ebi.ac.uk/pdbsum/6w10 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6w10 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/TREX1_MOUSE TREX1_MOUSE]] Exonuclease with a preference for double stranded DNA with mismatched 3' termini. May play a role in DNA repair.<ref>PMID:10391904</ref> <ref>PMID:11279105</ref>
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[https://www.uniprot.org/uniprot/TREX1_MOUSE TREX1_MOUSE] Exonuclease with a preference for double stranded DNA with mismatched 3' termini. May play a role in DNA repair.<ref>PMID:10391904</ref> <ref>PMID:11279105</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6w10" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6w10" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Exonuclease 3D structures|Exonuclease 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Exodeoxyribonuclease III]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lk3 transgenic mice]]
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[[Category: Mus musculus]]
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[[Category: Kranzusch, P J]]
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[[Category: Kranzusch PJ]]
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[[Category: Maciejowski, J]]
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[[Category: Maciejowski J]]
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[[Category: Mohr, L]]
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[[Category: Mohr L]]
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[[Category: Zhou, W]]
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[[Category: Zhou W]]
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[[Category: Autoimmunity]]
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[[Category: Dnase]]
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[[Category: Hydrolase]]
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[[Category: Innate immunity]]
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[[Category: Nuclease]]
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Current revision

Structure of mouse TREX1 with E198K disease-associated mutation

PDB ID 6w10

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