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Calculating GDT TS

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<span class="text-red">'''This page is under construction.''' [[User:Eric Martz|Eric Martz]] 01:18, 5 March 2021 (UTC)</span>
<span class="text-red">'''This page is under construction.''' [[User:Eric Martz|Eric Martz]] 01:18, 5 March 2021 (UTC)</span>
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The ''Global Distance Test - Total Score'' (GDT_TS) is used to quantitate the similarity between a predicted protein structure, and a reference structure, which is typically an [[empirical model]]. When the two structures differ in detail, GDT_TS is better at detecting similarities in fold than is the ''Root Mean Square Deviation''. Both tests compare the positions of only the alpha carbon atoms.
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The ''Global Distance Test - Total Score'' (GDT_TS) is used to quantitate the similarity between a predicted protein structure, and a reference structure, which is typically an [[empirical model]]. When the two structures differ in detail, GDT_TS is better at detecting similarities in fold than is the ''Root Mean Square Deviation''. Both tests compare the positions of only the alpha carbon atoms. Results of predictions submitted to the [[CASP|biannual CASP competitions]] are judged largely by GDT_TS.

Revision as of 18:21, 5 March 2021

This page is under construction. Eric Martz 01:18, 5 March 2021 (UTC)

The Global Distance Test - Total Score (GDT_TS) is used to quantitate the similarity between a predicted protein structure, and a reference structure, which is typically an empirical model. When the two structures differ in detail, GDT_TS is better at detecting similarities in fold than is the Root Mean Square Deviation. Both tests compare the positions of only the alpha carbon atoms. Results of predictions submitted to the biannual CASP competitions are judged largely by GDT_TS.

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