4iio
From Proteopedia
(Difference between revisions)
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<StructureSection load='4iio' size='340' side='right'caption='[[4iio]], [[Resolution|resolution]] 1.70Å' scene=''> | <StructureSection load='4iio' size='340' side='right'caption='[[4iio]], [[Resolution|resolution]] 1.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[4iio]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[4iio]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IIO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IIO FirstGlance]. <br> |
- | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand= | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> |
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4iio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4iio OCA], [https://pdbe.org/4iio PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4iio RCSB], [https://www.ebi.ac.uk/pdbsum/4iio PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4iio ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4iio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4iio OCA], [https://pdbe.org/4iio PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4iio RCSB], [https://www.ebi.ac.uk/pdbsum/4iio PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4iio ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
- | + | [https://www.uniprot.org/uniprot/ITSN2_HUMAN ITSN2_HUMAN] Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May regulate the formation of clathrin-coated vesicles (CCPs). Seems to be involved in CCPs maturation including invagination or budding. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR).<ref>PMID:19458185</ref> <ref>PMID:22648170</ref> | |
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
- | [[Category: Arrowsmith | + | [[Category: Arrowsmith CH]] |
- | [[Category: Bountra | + | [[Category: Bountra C]] |
- | [[Category: Dong | + | [[Category: Dong A]] |
- | [[Category: Edwards | + | [[Category: Edwards AM]] |
- | [[Category: Gu | + | [[Category: Gu J]] |
- | [[Category: Guan | + | [[Category: Guan X]] |
- | [[Category: Huang | + | [[Category: Huang H]] |
- | + | [[Category: Sidhu S]] | |
- | [[Category: Sidhu | + | [[Category: Tempel W]] |
- | [[Category: Tempel | + | [[Category: Tong Y]] |
- | [[Category: Tong | + | |
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Revision as of 10:41, 14 December 2022
Crystal Structure of the Second SH3 Domain of ITSN2 Bound with a Synthetic Peptide
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bountra C | Dong A | Edwards AM | Gu J | Guan X | Huang H | Sidhu S | Tempel W | Tong Y