2g4a

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Current revision (18:58, 29 May 2024) (edit) (undo)
 
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==Solution structure of a Bromodomain from RING3 protein==
==Solution structure of a Bromodomain from RING3 protein==
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<StructureSection load='2g4a' size='340' side='right'caption='[[2g4a]], [[NMR_Ensembles_of_Models | 21 NMR models]]' scene=''>
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<StructureSection load='2g4a' size='340' side='right'caption='[[2g4a]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2g4a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G4A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2G4A FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2g4a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G4A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2G4A FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RING3 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2g4a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g4a OCA], [https://pdbe.org/2g4a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2g4a RCSB], [https://www.ebi.ac.uk/pdbsum/2g4a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2g4a ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2g4a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g4a OCA], [https://pdbe.org/2g4a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2g4a RCSB], [https://www.ebi.ac.uk/pdbsum/2g4a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2g4a ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/BRD2_HUMAN BRD2_HUMAN]] May play a role in spermatogenesis or folliculogenesis (By similarity). Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly.<ref>PMID:18406326</ref>
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[https://www.uniprot.org/uniprot/BRD2_HUMAN BRD2_HUMAN] May play a role in spermatogenesis or folliculogenesis (By similarity). Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly.<ref>PMID:18406326</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Huang, H]]
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[[Category: Huang H]]
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[[Category: Shi, Y]]
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[[Category: Shi Y]]
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[[Category: Wu, J]]
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[[Category: Wu J]]
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[[Category: Gene regulation]]
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[[Category: Ring3 bromodomain]]
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Current revision

Solution structure of a Bromodomain from RING3 protein

PDB ID 2g4a

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