1dwq

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1dwq.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:1dwq.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1dwq| PDB=1dwq | SCENE= }}
{{STRUCTURE_1dwq| PDB=1dwq | SCENE= }}
-
'''CRYSTAL STRUCTURE OF HYDROXYNITRILE LYASE FROM MANIHOT ESCULENTA IN COMPLEX WITH SUBSTRATES ACETONE AND CHLOROACETONE:IMPLICATIONS FOR THE MECHANISM OF CYANOGENESIS'''
+
===CRYSTAL STRUCTURE OF HYDROXYNITRILE LYASE FROM MANIHOT ESCULENTA IN COMPLEX WITH SUBSTRATES ACETONE AND CHLOROACETONE:IMPLICATIONS FOR THE MECHANISM OF CYANOGENESIS===
-
==Overview==
+
<!--
-
The crystal structures of hydroxynitrile lyase from Manihot esculenta (MeHNL) complexed with the native substrate acetone and substrate analogue chloroacetone have been determined and refined at 2.2 A resolution. The substrates are positioned in the active site by hydrogen-bond interactions of the carbonyl O atom with Thr11 OG, Ser80 OG and, to a lesser extent, Cys81 SG. These studies support a mechanism for cyanogenesis as well as for the stereospecific MeHNL-catalyzed formation of (S)-cyanohydrins, which closely resembles the base-catalyzed chemical reaction of HCN with carbonyl compounds.
+
The line below this paragraph, {{ABSTRACT_PUBMED_11173464}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 11173464 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_11173464}}
==About this Structure==
==About this Structure==
Line 30: Line 34:
[[Category: Chloroacetone complex]]
[[Category: Chloroacetone complex]]
[[Category: Hydroxynitrile lyase]]
[[Category: Hydroxynitrile lyase]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 14:22:22 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 23:44:02 2008''

Revision as of 20:44, 30 June 2008

Image:1dwq.png

Template:STRUCTURE 1dwq

CRYSTAL STRUCTURE OF HYDROXYNITRILE LYASE FROM MANIHOT ESCULENTA IN COMPLEX WITH SUBSTRATES ACETONE AND CHLOROACETONE:IMPLICATIONS FOR THE MECHANISM OF CYANOGENESIS

Template:ABSTRACT PUBMED 11173464

About this Structure

1DWQ is a Single protein structure of sequence from Manihot esculenta. Full crystallographic information is available from OCA.

Reference

Structure of hydroxynitrile lyase from Manihot esculenta in complex with substrates acetone and chloroacetone: implications for the mechanism of cyanogenesis., Lauble H, Forster S, Miehlich B, Wajant H, Effenberger F, Acta Crystallogr D Biol Crystallogr. 2001 Feb;57(Pt 2):194-200. PMID:11173464

Page seeded by OCA on Mon Jun 30 23:44:02 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1dwq"
Personal tools