1dxz

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[[Image:1dxz.gif|left|200px]]
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{{STRUCTURE_1dxz| PDB=1dxz | SCENE= }}
{{STRUCTURE_1dxz| PDB=1dxz | SCENE= }}
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'''M2 TRANSMEMBRANE SEGMENT OF ALPHA-SUBUNIT OF NICOTINIC ACETYLCHOLINE RECEPTOR FROM TORPEDO CALIFORNICA, NMR, 20 STRUCTURES'''
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===M2 TRANSMEMBRANE SEGMENT OF ALPHA-SUBUNIT OF NICOTINIC ACETYLCHOLINE RECEPTOR FROM TORPEDO CALIFORNICA, NMR, 20 STRUCTURES===
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==Overview==
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A synthetic peptide corresponding to the transmembrane segment M2 (residues 236-267) of the alpha-subunit of the nicotinic acetylcholine receptor from Torpedo californica has been studied by two dimensional 1H-NMR spectroscopy in a chloroform-methanol (1:1) mixture containing 0.1 M LiClO4. Reconstruction of the spatial structure of M2 from the NMR data resulted in an alpha-helix formed by residues 241-263. Distribution of the molecular hydrophobicity potential on the helix surface is very similar to that in five-helix bundles of proteins with a known three dimensional structure: two hydrophilic bands located on the opposite helix sides separated by strong hydrophobic zones.
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(as it appears on PubMed at http://www.pubmed.gov), where 10486576 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10486576}}
==About this Structure==
==About this Structure==
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1DXZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Torpedo_californica Torpedo californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DXZ OCA].
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1DXZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Torpedo_californica Torpedo californica]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DXZ OCA].
==Reference==
==Reference==
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[[Category: Nicotinic acetylcholine receptor]]
[[Category: Nicotinic acetylcholine receptor]]
[[Category: Transmembrane segment]]
[[Category: Transmembrane segment]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 14:25:00 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 23:47:15 2008''

Revision as of 20:47, 30 June 2008

Image:1dxz.png

Template:STRUCTURE 1dxz

M2 TRANSMEMBRANE SEGMENT OF ALPHA-SUBUNIT OF NICOTINIC ACETYLCHOLINE RECEPTOR FROM TORPEDO CALIFORNICA, NMR, 20 STRUCTURES

Template:ABSTRACT PUBMED 10486576

About this Structure

1DXZ is a Single protein structure of sequence from Torpedo californica. Full experimental information is available from OCA.

Reference

Spatial structure of the M2 transmembrane segment of the nicotinic acetylcholine receptor alpha-subunit., Pashkov VS, Maslennikov IV, Tchikin LD, Efremov RG, Ivanov VT, Arseniev AS, FEBS Lett. 1999 Aug 20;457(1):117-21. PMID:10486576

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