7lvc
From Proteopedia
(Difference between revisions)
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==E. coli DHFR by Native Mn,P,S-SAD at Room Temperature== | ==E. coli DHFR by Native Mn,P,S-SAD at Room Temperature== | ||
| - | <StructureSection load='7lvc' size='340' side='right'caption='[[7lvc]]' scene=''> | + | <StructureSection load='7lvc' size='340' side='right'caption='[[7lvc]], [[Resolution|resolution]] 1.70Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7LVC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7LVC FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7lvc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7LVC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7LVC FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lvc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lvc OCA], [https://pdbe.org/7lvc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lvc RCSB], [https://www.ebi.ac.uk/pdbsum/7lvc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lvc ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FOL:FOLIC+ACID'>FOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> |
| + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene></td></tr> | ||
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[7l84|7l84]]</div></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">folA, tmrA, b0048, JW0047 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lvc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lvc OCA], [https://pdbe.org/7lvc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lvc RCSB], [https://www.ebi.ac.uk/pdbsum/7lvc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lvc ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/DYR_ECOLI DYR_ECOLI]] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Dihydrofolate reductase]] | ||
| + | [[Category: Ecoli]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Dalton | + | [[Category: Dalton, K M]] |
| - | [[Category: Greisman | + | [[Category: Greisman, J B]] |
| - | [[Category: Hekstra | + | [[Category: Hekstra, D R]] |
| + | [[Category: Oxidoreductase]] | ||
Revision as of 04:59, 3 August 2022
E. coli DHFR by Native Mn,P,S-SAD at Room Temperature
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