1hez
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1hez]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Finegoldia_magna Finegoldia magna] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HEZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HEZ FirstGlance]. <br> | <table><tr><td colspan='2'>[[1hez]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Finegoldia_magna Finegoldia magna] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HEZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HEZ FirstGlance]. <br> | ||
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hez OCA], [https://pdbe.org/1hez PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hez RCSB], [https://www.ebi.ac.uk/pdbsum/1hez PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hez ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hez OCA], [https://pdbe.org/1hez PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hez RCSB], [https://www.ebi.ac.uk/pdbsum/1hez PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hez ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/IGKC_HUMAN IGKC_HUMAN] Defects in IGKC are the cause of immunoglobulin kappa light chain deficiency (IGKCD) [MIM:[https://omim.org/entry/614102 614102]. IGKCD is a disease characterized by the complete absence of immunoglobulin kappa chains.<ref>PMID:3931219</ref> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/IGKC_HUMAN IGKC_HUMAN] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Bottomley | + | [[Category: Bottomley SP]] |
| - | [[Category: Charbonnier | + | [[Category: Charbonnier JB]] |
| - | [[Category: Gore | + | [[Category: Gore MG]] |
| - | [[Category: Graille | + | [[Category: Graille M]] |
| - | [[Category: Housden | + | [[Category: Housden NG]] |
| - | [[Category: Stura | + | [[Category: Stura EA]] |
| - | [[Category: Sutton | + | [[Category: Sutton BJ]] |
| - | [[Category: Taussig | + | [[Category: Taussig MJ]] |
| - | + | ||
| - | + | ||
Revision as of 12:24, 13 December 2023
Structure of P. magnus protein L bound to a human IgM Fab.
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