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7cly

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Current revision (16:10, 29 November 2023) (edit) (undo)
 
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<StructureSection load='7cly' size='340' side='right'caption='[[7cly]], [[Resolution|resolution]] 1.43&Aring;' scene=''>
<StructureSection load='7cly' size='340' side='right'caption='[[7cly]], [[Resolution|resolution]] 1.43&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[7cly]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CLY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CLY FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7cly]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CLY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CLY FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[7clx|7clx]]</div></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.432&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Dock8 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7cly FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cly OCA], [https://pdbe.org/7cly PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7cly RCSB], [https://www.ebi.ac.uk/pdbsum/7cly PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7cly ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7cly FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cly OCA], [https://pdbe.org/7cly PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7cly RCSB], [https://www.ebi.ac.uk/pdbsum/7cly PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7cly ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/DOCK8_MOUSE DOCK8_MOUSE]] Potential guanine nucleotide exchange factor (GEF). GEF proteins activate some small GTPases by exchanging bound GDP for free GTP (By similarity).
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[https://www.uniprot.org/uniprot/DOCK8_MOUSE DOCK8_MOUSE] Potential guanine nucleotide exchange factor (GEF). GEF proteins activate some small GTPases by exchanging bound GDP for free GTP (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 7cly" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 7cly" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Dedicator of cytokinesis protein 3D structures|Dedicator of cytokinesis protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lk3 transgenic mice]]
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[[Category: Mus musculus]]
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[[Category: Fukui, Y]]
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[[Category: Fukui Y]]
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[[Category: Kukimoto-Niino, M]]
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[[Category: Kukimoto-Niino M]]
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[[Category: Shirouzu, M]]
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[[Category: Shirouzu M]]
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[[Category: Uruno, T]]
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[[Category: Uruno T]]
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[[Category: Yokoyama, S]]
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[[Category: Yokoyama S]]
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[[Category: Cdc42]]
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[[Category: Dock]]
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[[Category: Gtpase]]
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[[Category: Guanine nucleotide exchange factor]]
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[[Category: Membrane]]
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[[Category: Phosphoinositide]]
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[[Category: Signaling protein]]
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Current revision

Structure of the DOCK8 DHR-1 domain crystallized with di-C8-phosphatidylinositol-(4,5)-bisphosphate

PDB ID 7cly

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