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2hfh
From Proteopedia
(Difference between revisions)
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==THE NMR STRUCTURES OF A WINGED HELIX PROTEIN: GENESIS, 20 STRUCTURES== | ==THE NMR STRUCTURES OF A WINGED HELIX PROTEIN: GENESIS, 20 STRUCTURES== | ||
| - | <StructureSection load='2hfh' size='340' side='right'caption='[[2hfh | + | <StructureSection load='2hfh' size='340' side='right'caption='[[2hfh]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2hfh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2hfh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HFH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HFH FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hfh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hfh OCA], [https://pdbe.org/2hfh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hfh RCSB], [https://www.ebi.ac.uk/pdbsum/2hfh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hfh ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hfh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hfh OCA], [https://pdbe.org/2hfh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hfh RCSB], [https://www.ebi.ac.uk/pdbsum/2hfh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hfh ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/FOXD3_RAT FOXD3_RAT] Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis (By similarity). | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Buffalo rat]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Rattus norvegicus]] |
| - | [[Category: | + | [[Category: Jin C]] |
| - | [[Category: | + | [[Category: Liao X]] |
| - | [[Category: | + | [[Category: Marsden I]] |
| - | + | ||
Current revision
THE NMR STRUCTURES OF A WINGED HELIX PROTEIN: GENESIS, 20 STRUCTURES
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