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2i80

From Proteopedia

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Current revision (10:07, 30 August 2023) (edit) (undo)
 
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<StructureSection load='2i80' size='340' side='right'caption='[[2i80]], [[Resolution|resolution]] 2.19&Aring;' scene=''>
<StructureSection load='2i80' size='340' side='right'caption='[[2i80]], [[Resolution|resolution]] 2.19&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2i80]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I80 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I80 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2i80]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I80 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I80 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=G1L:3-CHLORO-2,2-DIMETHYL-N-[4-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE'>G1L</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.19&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ddl, ddlA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 "Micrococcus aureus" (Rosenbach 1884) Zopf 1885])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=G1L:3-CHLORO-2,2-DIMETHYL-N-[4-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE'>G1L</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/D-alanine--D-alanine_ligase D-alanine--D-alanine ligase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.4 6.3.2.4] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i80 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i80 OCA], [https://pdbe.org/2i80 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i80 RCSB], [https://www.ebi.ac.uk/pdbsum/2i80 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i80 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i80 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i80 OCA], [https://pdbe.org/2i80 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i80 RCSB], [https://www.ebi.ac.uk/pdbsum/2i80 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i80 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/DDL_STAAC DDL_STAAC]] Cell wall formation (By similarity).
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[https://www.uniprot.org/uniprot/DDL_STAAC DDL_STAAC] Cell wall formation (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: D-alanine--D-alanine ligase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Chang, J S]]
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[[Category: Staphylococcus aureus]]
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[[Category: Herberg, J T]]
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[[Category: Chang JS]]
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[[Category: Horng, M M]]
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[[Category: Herberg JT]]
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[[Category: Lin, A H]]
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[[Category: Horng M-M]]
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[[Category: Liu, S]]
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[[Category: Lin AH]]
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[[Category: Marotti, K R]]
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[[Category: Liu S]]
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[[Category: Tomich, P K]]
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[[Category: Marotti KR]]
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[[Category: Ligase]]
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[[Category: Tomich PK]]
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[[Category: Protein-inhibitor complex]]
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Current revision

Allosteric inhibition of Staphylococcus aureus D-alanine:D-alanine ligase revealed by crystallographic studies

PDB ID 2i80

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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