User:Hannah Wright/Sandbox 1
From Proteopedia
(Difference between revisions)
| Line 17: | Line 17: | ||
<scene name='87/877603/Catalytic_triad/1'>Catalytic Triad</scene> | <scene name='87/877603/Catalytic_triad/1'>Catalytic Triad</scene> | ||
== Disease == | == Disease == | ||
| + | ===Mutations=== | ||
| + | ====D201V==== | ||
| + | ====M404R==== | ||
[https://www.webmd.com/cholesterol-management/hyperlipidemia-overview Hyperlipidemia] | [https://www.webmd.com/cholesterol-management/hyperlipidemia-overview Hyperlipidemia] | ||
== Relevance == | == Relevance == | ||
| - | + | ===Hypertriglycerademia=== | |
| + | ===Drug Relevance=== | ||
== Structural highlights == | == Structural highlights == | ||
</StructureSection> | </StructureSection> | ||
| - | + | ===Overall Structure=== | |
| + | ===LPL=== | ||
| + | ===GPIHBP1=== | ||
| + | Calcium Ion Coordination=== | ||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 18:33, 30 March 2021
Contents |
Lipoprotein Lipase (LPL) complexed with GPIHBP1
| |||||||||||
Overall Structure
LPL
GPIHBP1
Calcium Ion Coordination===
References
- ↑ Birrane G, Beigneux AP, Dwyer B, Strack-Logue B, Kristensen KK, Francone OL, Fong LG, Mertens HDT, Pan CQ, Ploug M, Young SG, Meiyappan M. Structure of the lipoprotein lipase-GPIHBP1 complex that mediates plasma triglyceride hydrolysis. Proc Natl Acad Sci U S A. 2018 Dec 17. pii: 1817984116. doi:, 10.1073/pnas.1817984116. PMID:30559189 doi:http://dx.doi.org/10.1073/pnas.1817984116
Student/Contributors
- Ashrey Burely
- Allison Welz
- Hannah Wright
