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6w9z
From Proteopedia
(Difference between revisions)
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==De novo designed receptor transmembrane domains enhance CAR-T cytotoxicity and attenuate cytokine release== | ==De novo designed receptor transmembrane domains enhance CAR-T cytotoxicity and attenuate cytokine release== | ||
| - | <StructureSection load='6w9z' size='340' side='right'caption='[[6w9z]]' scene=''> | + | <StructureSection load='6w9z' size='340' side='right'caption='[[6w9z]], [[Resolution|resolution]] 2.70Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6W9Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6W9Z FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6w9z]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct_sequences Synthetic construct sequences]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6W9Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6W9Z FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6w9z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6w9z OCA], [https://pdbe.org/6w9z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6w9z RCSB], [https://www.ebi.ac.uk/pdbsum/6w9z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6w9z ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OLB:(2S)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLB</scene></td></tr> |
| + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SCH:S-METHYL-THIO-CYSTEINE'>SCH</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6w9z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6w9z OCA], [https://pdbe.org/6w9z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6w9z RCSB], [https://www.ebi.ac.uk/pdbsum/6w9z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6w9z ProSAT]</span></td></tr> | ||
</table> | </table> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Call | + | [[Category: Synthetic construct sequences]] |
| - | [[Category: Call | + | [[Category: Call, M E]] |
| - | [[Category: Chandler | + | [[Category: Call, M J]] |
| - | [[Category: Nguyen | + | [[Category: Chandler, N J]] |
| - | [[Category: Trenker R]] | + | [[Category: Nguyen, J V]] |
| + | [[Category: Trenker, R]] | ||
| + | [[Category: Biosynthetic protein]] | ||
| + | [[Category: De novo design]] | ||
| + | [[Category: Transmembrane domain]] | ||
Revision as of 14:52, 17 June 2021
De novo designed receptor transmembrane domains enhance CAR-T cytotoxicity and attenuate cytokine release
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