6yav
From Proteopedia
(Difference between revisions)
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==Structure of FeSII (Shethna) protein from Azotobacter vinelandii== | ==Structure of FeSII (Shethna) protein from Azotobacter vinelandii== | ||
- | <StructureSection load='6yav' size='340' side='right'caption='[[6yav]]' scene=''> | + | <StructureSection load='6yav' size='340' side='right'caption='[[6yav]], [[Resolution|resolution]] 1.65Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6YAV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6YAV FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6yav]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Azotobacter_vinelandii Azotobacter vinelandii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6YAV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6YAV FirstGlance]. <br> |
- | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6yav FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6yav OCA], [https://pdbe.org/6yav PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6yav RCSB], [https://www.ebi.ac.uk/pdbsum/6yav PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6yav ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65Å</td></tr> |
+ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6yav FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6yav OCA], [https://pdbe.org/6yav PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6yav RCSB], [https://www.ebi.ac.uk/pdbsum/6yav PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6yav ProSAT]</span></td></tr> | ||
</table> | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/FESII_AZOVI FESII_AZOVI] Binds to and protects nitrogenase from irreversible exposure to O(2), in what is known as 'conformational protection' (PubMed:7830548, PubMed:7548055, PubMed:10220344, PubMed:26654855). Shifts nitrogenase into an inactive, O(2)-tolerant state. Exists in 2 states, an open oxidized state that binds and protects nitrogenase, and a closed reduced state that probably does not bind nitrogenase; cooperative oxidation of the 2Fe-2S clusters causes the conformation change (PubMed:26654855). Does not protect nitrogenase with the vanadium-iron subunit, not clear if it protects the iron-only nitrogenase (PubMed:7830548).<ref>PMID:10220344</ref> <ref>PMID:26654855</ref> <ref>PMID:7548055</ref> <ref>PMID:7830548</ref> | ||
+ | == References == | ||
+ | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
+ | [[Category: Azotobacter vinelandii]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Cotton CAR]] | [[Category: Cotton CAR]] |
Current revision
Structure of FeSII (Shethna) protein from Azotobacter vinelandii
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