7brh

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==Atrial Natriuretic Peptide Receptor complexed with human Atrial Natriuretic Peptide==
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<StructureSection load='7brh' size='340' side='right'caption='[[7brh]]' scene=''>
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<StructureSection load='7brh' size='340' side='right'caption='[[7brh]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7brh]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BRH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BRH FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7brh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7brh OCA], [https://pdbe.org/7brh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7brh RCSB], [https://www.ebi.ac.uk/pdbsum/7brh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7brh ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7brh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7brh OCA], [https://pdbe.org/7brh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7brh RCSB], [https://www.ebi.ac.uk/pdbsum/7brh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7brh ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ANPRA_RAT ANPRA_RAT] Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand (By similarity).
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Z-disk]]
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[[Category: Rattus norvegicus]]
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[[Category: Ogawa H]]

Revision as of 15:27, 29 November 2023

Atrial Natriuretic Peptide Receptor complexed with human Atrial Natriuretic Peptide

PDB ID 7brh

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