7jg4

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Current revision (15:02, 18 October 2023) (edit) (undo)
 
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==Human GAR transformylase in complex with GAR substrate and AGF131 inhibitor==
==Human GAR transformylase in complex with GAR substrate and AGF131 inhibitor==
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<StructureSection load='7jg4' size='340' side='right'caption='[[7jg4]]' scene=''>
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<StructureSection load='7jg4' size='340' side='right'caption='[[7jg4]], [[Resolution|resolution]] 2.46&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7JG4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7JG4 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7jg4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7JG4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7JG4 FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7jg4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7jg4 OCA], [https://pdbe.org/7jg4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7jg4 RCSB], [https://www.ebi.ac.uk/pdbsum/7jg4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7jg4 ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.455&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GAR:GLYCINAMIDE+RIBONUCLEOTIDE'>GAR</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=V9V:N-(5-{3-[(1S,7R,8R,9S)-4-amino-2-oxo-7lambda~4~-thia-3,5-diazatetracyclo[4.3.0.0~1,7~.0~7,9~]nona-3,5-dien-8-yl]propyl}thiophene-2-carbonyl)-L-glutamic+acid'>V9V</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7jg4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7jg4 OCA], [https://pdbe.org/7jg4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7jg4 RCSB], [https://www.ebi.ac.uk/pdbsum/7jg4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7jg4 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PUR2_HUMAN PUR2_HUMAN]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Dann III CE]]
[[Category: Dann III CE]]
[[Category: Wong-Roushar J]]
[[Category: Wong-Roushar J]]

Current revision

Human GAR transformylase in complex with GAR substrate and AGF131 inhibitor

PDB ID 7jg4

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