This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3plc
From Proteopedia
(Difference between revisions)
| Line 7: | Line 7: | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/3SDC7_OPHHA 3SDC7_OPHHA] Acts as a beta-blocker by binding to beta-1 and beta-2 adrenergic receptors (ADRB1 and ADRB2). It dose-dependently decreases the heart rate (bradycardia), whereas conventional cardiotoxins increases it. At 100 mg/kg, intraperitoneal injection into mice provokes labored breathing, impaired locomotion, lack of response to external stimuli, and death (after 30 min).<ref>PMID:17616557</ref> | |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 26: | Line 26: | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Ophiophagus hannah]] | [[Category: Ophiophagus hannah]] | ||
| - | [[Category: Kini | + | [[Category: Kini RM]] |
| - | [[Category: Qingxiang | + | [[Category: Qingxiang S]] |
| - | [[Category: Roy | + | [[Category: Roy A]] |
| - | [[Category: Sivaraman | + | [[Category: Sivaraman J]] |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Revision as of 08:08, 11 January 2023
Crystal structure of Beta-Cardiotoxin, a novel three-finger cardiotoxin from the venom of Ophiophagus hannah
| |||||||||||
