2ig7
From Proteopedia
(Difference between revisions)
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<StructureSection load='2ig7' size='340' side='right'caption='[[2ig7]], [[Resolution|resolution]] 1.80Å' scene=''> | <StructureSection load='2ig7' size='340' side='right'caption='[[2ig7]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2ig7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2ig7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IG7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IG7 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ig7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ig7 OCA], [https://pdbe.org/2ig7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ig7 RCSB], [https://www.ebi.ac.uk/pdbsum/2ig7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ig7 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ig7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ig7 OCA], [https://pdbe.org/2ig7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ig7 RCSB], [https://www.ebi.ac.uk/pdbsum/2ig7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ig7 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | == Function == | ||
| - | [[https://www.uniprot.org/uniprot/CHKB_HUMAN CHKB_HUMAN]] Has a key role in phospholipid biosynthesis. Catalyzes the first step in phosphatidylethanolamine biosynthesis. Phosphorylates ethanolamine, and can also act on choline (in vitro). Has higher activity with ethanolamine. May not significantly contribute to in vivo phosphatidylcholine biosynthesis.<ref>PMID:19915674</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ig/2ig7_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ig/2ig7_consurf.spt"</scriptWhenChecked> | ||
| - | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> |
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
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==See Also== | ==See Also== | ||
*[[Choline kinase 3D structures|Choline kinase 3D structures]] | *[[Choline kinase 3D structures|Choline kinase 3D structures]] | ||
| - | == References == | ||
| - | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
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[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Arrowsmith | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Bochkarev | + | [[Category: Bochkarev A]] |
| - | [[Category: Edwards | + | [[Category: Edwards AM]] |
| - | [[Category: Landry | + | [[Category: Landry R]] |
| - | [[Category: Nedyalkova | + | [[Category: Nedyalkova L]] |
| - | [[Category: Park | + | [[Category: Park H]] |
| - | [[Category: Rabeh | + | [[Category: Rabeh WM]] |
| - | + | [[Category: Sundstrom M]] | |
| - | [[Category: Sundstrom | + | [[Category: Tempel W]] |
| - | [[Category: Tempel | + | [[Category: Vedadi M]] |
| - | [[Category: Vedadi | + | [[Category: Wasney G]] |
| - | [[Category: Wasney | + | [[Category: Weigelt J]] |
| - | [[Category: Weigelt | + | |
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Current revision
Crystal structure of Human Choline Kinase B
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bochkarev A | Edwards AM | Landry R | Nedyalkova L | Park H | Rabeh WM | Sundstrom M | Tempel W | Vedadi M | Wasney G | Weigelt J
