2iqj

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Current revision (10:15, 30 August 2023) (edit) (undo)
 
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<StructureSection load='2iqj' size='340' side='right'caption='[[2iqj]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='2iqj' size='340' side='right'caption='[[2iqj]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2iqj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IQJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IQJ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2iqj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IQJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IQJ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SMAP1L ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iqj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iqj OCA], [https://pdbe.org/2iqj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iqj RCSB], [https://www.ebi.ac.uk/pdbsum/2iqj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iqj ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iqj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iqj OCA], [https://pdbe.org/2iqj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iqj RCSB], [https://www.ebi.ac.uk/pdbsum/2iqj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iqj ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/SMAP2_HUMAN SMAP2_HUMAN]] GTPase activating protein that acts on ARF1. Can also activate ARF6 (in vitro). May play a role in clathrin-dependent retrograde transport from early endosomes to the trans-Golgi network (By similarity).
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[https://www.uniprot.org/uniprot/SMAP2_HUMAN SMAP2_HUMAN] GTPase activating protein that acts on ARF1. Can also activate ARF6 (in vitro). May play a role in clathrin-dependent retrograde transport from early endosomes to the trans-Golgi network (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Arrowsmith, C H]]
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[[Category: Arrowsmith CH]]
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[[Category: Bochkarev, A]]
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[[Category: Bochkarev A]]
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[[Category: Dimov, S]]
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[[Category: Dimov S]]
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[[Category: Edwards, A M]]
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[[Category: Edwards AM]]
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[[Category: Landry, R]]
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[[Category: Landry R]]
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[[Category: Park, H]]
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[[Category: Park H]]
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[[Category: Structural genomic]]
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[[Category: Shen L]]
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[[Category: Shen, L]]
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[[Category: Sundstrom M]]
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[[Category: Sundstrom, M]]
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[[Category: Tempel W]]
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[[Category: Tempel, W]]
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[[Category: Tong Y]]
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[[Category: Tong, Y]]
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[[Category: Weigelt J]]
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[[Category: Weigelt, J]]
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[[Category: Membrane-associated]]
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[[Category: Protein transport]]
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[[Category: Sgc]]
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[[Category: Stromal]]
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[[Category: Zinc]]
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Current revision

Crystal structure of the GAP domain of SMAP1L (LOC64744) stromal membrane-associated protein 1-like

PDB ID 2iqj

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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