This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5cgb

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 3: Line 3:
<StructureSection load='5cgb' size='340' side='right'caption='[[5cgb]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='5cgb' size='340' side='right'caption='[[5cgb]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5cgb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CGB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CGB FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5cgb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CGB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CGB FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=51C:(6R)-1,6-ANHYDRO-2-O-HEPTYL-6-(HYDROXYMETHYL)-D-GALACTITOL'>51C</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=51C:(6R)-1,6-ANHYDRO-2-O-HEPTYL-6-(HYDROXYMETHYL)-D-GALACTITOL'>51C</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fimH, b4320, JW4283 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5cgb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cgb OCA], [https://pdbe.org/5cgb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5cgb RCSB], [https://www.ebi.ac.uk/pdbsum/5cgb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5cgb ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5cgb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cgb OCA], [https://pdbe.org/5cgb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5cgb RCSB], [https://www.ebi.ac.uk/pdbsum/5cgb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5cgb ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[https://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI]] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed.
+
[https://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 26: Line 25:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Ecoli]]
+
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Ernst, B]]
+
[[Category: Ernst B]]
-
[[Category: Fiege, B]]
+
[[Category: Fiege B]]
-
[[Category: Jakob, R P]]
+
[[Category: Jakob RP]]
-
[[Category: Maier, T]]
+
[[Category: Maier T]]
-
[[Category: Peczuh, M]]
+
[[Category: Peczuh M]]
-
[[Category: Preston, R P]]
+
[[Category: Preston RP]]
-
[[Category: Rabbani, S]]
+
[[Category: Rabbani S]]
-
[[Category: Sager, C P]]
+
[[Category: Sager CP]]
-
[[Category: Vannam, R]]
+
[[Category: Vannam R]]
-
[[Category: Zalewski, A]]
+
[[Category: Zalewski A]]
-
[[Category: Zihlmann, P]]
+
[[Category: Zihlmann P]]
-
[[Category: Inhibitor]]
+
-
[[Category: Lectin]]
+
-
[[Category: Pilus]]
+
-
[[Category: Sugar binding protein]]
+
-
[[Category: Type 1 fimbriae]]
+
-
[[Category: Urinary tract infection]]
+
-
[[Category: Uti]]
+

Revision as of 12:04, 14 June 2023

Crystal structure of FimH in complex with heptyl alpha-D-septanoside

PDB ID 5cgb

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5cgb"
Personal tools