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| - | | + | #REDIRECT [[7oj4]] This PDB entry is obsolete and replaced by 7oj4 |
| - | ==Crystal structure of the tick-borne encephalitis virus NS3 helicase (apo form).==
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| - | <StructureSection load='7ay4' size='340' side='right'caption='[[7ay4]], [[Resolution|resolution]] 1.83Å' scene=''>
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| - | == Structural highlights ==
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| - | <table><tr><td colspan='2'>[[7ay4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Fsme_virus Fsme virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7AY4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7AY4 FirstGlance]. <br>
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| - | </td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/RNA_helicase RNA helicase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.13 3.6.4.13] </span></td></tr>
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| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ay4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ay4 OCA], [https://pdbe.org/7ay4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ay4 RCSB], [https://www.ebi.ac.uk/pdbsum/7ay4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ay4 ProSAT]</span></td></tr>
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| - | </table>
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| - | == Function ==
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| - | [[https://www.uniprot.org/uniprot/A0A2S1PWV0_9FLAV A0A2S1PWV0_9FLAV]] Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter.[ARBA:ARBA00003504] Serine protease subunit NS2B: Required cofactor for the serine protease function of NS3.[PROSITE-ProRule:PRU00859]
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| - | __TOC__
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| - | </StructureSection>
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| - | [[Category: Fsme virus]]
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| - | [[Category: Large Structures]]
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| - | [[Category: RNA helicase]]
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| - | [[Category: Anindita, P D]]
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| - | [[Category: Brynda, J]]
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| - | [[Category: Franta, Z]]
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| - | [[Category: Havlickova, P]]
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| - | [[Category: Kascakova, B]]
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| - | [[Category: Hydrolase]]
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| - | [[Category: Rna helicase]]
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| - | [[Category: Viral protein]]
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