This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


7b9z

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (12:24, 1 February 2024) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='7b9z' size='340' side='right'caption='[[7b9z]], [[Resolution|resolution]] 1.44&Aring;' scene=''>
<StructureSection load='7b9z' size='340' side='right'caption='[[7b9z]], [[Resolution|resolution]] 1.44&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[7b9z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7B9Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7B9Z FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[7b9z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7B9Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7B9Z FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IS8:isothiocyanate'>IS8</scene>, <scene name='pdbligand=T58:2-cyclohexyl-12-[2-(3,4-dimethoxyphenyl)ethyl]-25,26-dimethoxy-11,18,23-trioxa-4-azatetracyclo[22.3.1.113,17.04,9]nonacosa-1(27),13(29),14,16,20,24(28),25-heptaene-3,10-dione'>T58</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.44&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FKBP5, AIG6, FKBP51 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IS8:isothiocyanate'>IS8</scene>, <scene name='pdbligand=T58:2-cyclohexyl-12-[2-(3,4-dimethoxyphenyl)ethyl]-25,26-dimethoxy-11,18,23-trioxa-4-azatetracyclo[22.3.1.113,17.04,9]nonacosa-1(27),13(29),14,16,20,24(28),25-heptaene-3,10-dione'>T58</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7b9z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7b9z OCA], [https://pdbe.org/7b9z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7b9z RCSB], [https://www.ebi.ac.uk/pdbsum/7b9z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7b9z ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7b9z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7b9z OCA], [https://pdbe.org/7b9z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7b9z RCSB], [https://www.ebi.ac.uk/pdbsum/7b9z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7b9z ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[https://www.uniprot.org/uniprot/FKBP5_HUMAN FKBP5_HUMAN]] Interacts with functionally mature heterooligomeric progesterone receptor complexes along with HSP90 and TEBP.
+
[https://www.uniprot.org/uniprot/FKBP5_HUMAN FKBP5_HUMAN] Interacts with functionally mature heterooligomeric progesterone receptor complexes along with HSP90 and TEBP.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 20: Line 19:
</div>
</div>
<div class="pdbe-citations 7b9z" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 7b9z" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[FKBP 3D structures|FKBP 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Peptidylprolyl isomerase]]
+
[[Category: Bauder M]]
-
[[Category: Bauder, M]]
+
[[Category: Hausch F]]
-
[[Category: Hausch, F]]
+
[[Category: Heymann T]]
-
[[Category: Heymann, T]]
+
[[Category: Merz S]]
-
[[Category: Merz, S]]
+
[[Category: Meyners C]]
-
[[Category: Meyners, C]]
+
[[Category: Purder P]]
-
[[Category: Purder, P]]
+
[[Category: Voll A]]
-
[[Category: Voll, A]]
+
-
[[Category: Complex]]
+
-
[[Category: Fkbp]]
+
-
[[Category: Inhibitor]]
+
-
[[Category: Isomerase]]
+
-
[[Category: Safit]]
+

Current revision

Structure of the FKBP51FK1 domain in complex with the macrocyclic SAFit analogue 35-(E)

PDB ID 7b9z

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools