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1i9a
From Proteopedia
(Difference between revisions)
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==STRUCTURAL STUDIES OF CHOLESTEROL BIOSYNTHESIS: MEVALONATE 5-DIPHOSPHATE DECARBOXYLASE AND ISOPENTENYL DIPHOSPHATE ISOMERASE== | ==STRUCTURAL STUDIES OF CHOLESTEROL BIOSYNTHESIS: MEVALONATE 5-DIPHOSPHATE DECARBOXYLASE AND ISOPENTENYL DIPHOSPHATE ISOMERASE== | ||
| - | <StructureSection load='1i9a' size='340' side='right'caption='[[1i9a]]' scene=''> | + | <StructureSection load='1i9a' size='340' side='right'caption='[[1i9a]], [[Resolution|resolution]] 2.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I9A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1I9A FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[1i9a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I9A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1I9A FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1i9a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i9a OCA], [https://pdbe.org/1i9a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1i9a RCSB], [https://www.ebi.ac.uk/pdbsum/1i9a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1i9a ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1i9a TOPSAN]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1i9a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i9a OCA], [https://pdbe.org/1i9a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1i9a RCSB], [https://www.ebi.ac.uk/pdbsum/1i9a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1i9a ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1i9a TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/IDI_ECOLI IDI_ECOLI] Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).<ref>PMID:10099534</ref> <ref>PMID:9603997</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
*[[Isopentenyl-diphosphate delta-isomerase|Isopentenyl-diphosphate delta-isomerase]] | *[[Isopentenyl-diphosphate delta-isomerase|Isopentenyl-diphosphate delta-isomerase]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Escherichia coli]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Bonanno JB]] | [[Category: Bonanno JB]] | ||
Current revision
STRUCTURAL STUDIES OF CHOLESTEROL BIOSYNTHESIS: MEVALONATE 5-DIPHOSPHATE DECARBOXYLASE AND ISOPENTENYL DIPHOSPHATE ISOMERASE
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Categories: Escherichia coli | Large Structures | Bonanno JB | Burley SK | Edo C | Eswar N | Gerchman SE | Ilyin V | Kycia H | Pieper U | Romanowski MJ | Sali A | Studier FW
