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2k0d
From Proteopedia
(Difference between revisions)
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==NMR structure of a mutant colicin e7 immunity protein im7 with an extended helix III== | ==NMR structure of a mutant colicin e7 immunity protein im7 with an extended helix III== | ||
| - | <StructureSection load='2k0d' size='340' side='right'caption='[[2k0d | + | <StructureSection load='2k0d' size='340' side='right'caption='[[2k0d]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2k0d]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K0D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K0D FirstGlance]. <br> | <table><tr><td colspan='2'>[[2k0d]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K0D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K0D FirstGlance]. <br> | ||
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k0d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k0d OCA], [https://pdbe.org/2k0d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k0d RCSB], [https://www.ebi.ac.uk/pdbsum/2k0d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k0d ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k0d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k0d OCA], [https://pdbe.org/2k0d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k0d RCSB], [https://www.ebi.ac.uk/pdbsum/2k0d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k0d ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/IMM7_ECOLX IMM7_ECOLX] This protein is able to protect a cell, which harbors the plasmid ColE7 encoding colicin E7, against colicin E7, it binds specifically to the DNase-type colicin and inhibits its bactericidal activity. Dimeric ImmE7 may possess a RNase activity that cleaves its own mRNA at a specific site and thus autoregulates translational expression of the downstream ceiE7 gene as well as degradation of the upstream ceaE7 mRNA. | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Figueiredo | + | [[Category: Figueiredo AM]] |
| - | [[Category: Knowling | + | [[Category: Knowling SE]] |
| - | [[Category: Moore | + | [[Category: Moore GR]] |
| - | [[Category: Radford | + | [[Category: Radford SE]] |
| - | [[Category: Spronk | + | [[Category: Spronk CA]] |
| - | [[Category: Whittaker | + | [[Category: Whittaker SB]] |
| - | + | ||
| - | + | ||
Current revision
NMR structure of a mutant colicin e7 immunity protein im7 with an extended helix III
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