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6ya2

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Current revision (13:22, 24 January 2024) (edit) (undo)
 
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<StructureSection load='6ya2' size='340' side='right'caption='[[6ya2]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='6ya2' size='340' side='right'caption='[[6ya2]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6ya2]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Tswv Tswv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6YA2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6YA2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6ya2]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Tomato_spotted_wilt_orthotospovirus Tomato spotted wilt orthotospovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6YA2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6YA2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[6y9l|6y9l]], [[6y9m|6y9m]], [[6ya0|6ya0]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Gn, Gc ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1933298 TSWV])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ya2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ya2 OCA], [https://pdbe.org/6ya2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ya2 RCSB], [https://www.ebi.ac.uk/pdbsum/6ya2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ya2 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ya2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ya2 OCA], [https://pdbe.org/6ya2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ya2 RCSB], [https://www.ebi.ac.uk/pdbsum/6ya2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ya2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/A0A3G1GK10_TSWV A0A3G1GK10_TSWV]] Together with Glycoprotein C are present at the surface of the virion. They are able to attach the virion to a cell receptor and to promote fusion of membranes after endocytosis of the virion.[ARBA:ARBA00002373] Together with Glycoprotein N are present at the surface of the virion. They are able to attach the virion to a cell receptor and to promote fusion of membranes after endocytosis of the virion.[ARBA:ARBA00004076]
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[https://www.uniprot.org/uniprot/GP_TSWV1 GP_TSWV1] Forms the spikes present at the surface of the virion together with Glycoprotein C. They are able to attach the virion to a cell receptor and to promote fusion of membranes after endocytosis of the virion (By similarity). Plays a role in virus binding and/or entry into the vector midgut (PubMed:31413126).[UniProtKB:P08668]<ref>PMID:31413126</ref> Forms the spikes present at the surface of the virion together with Glycoprotein N. They are able to attach the virion to a cell receptor and to promote fusion of membranes after endocytosis of the virion (By similarity). Probable class II fusion protein (PubMed:33672327).[UniProtKB:P08668]<ref>PMID:33672327</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Tswv]]
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[[Category: Tomato spotted wilt orthotospovirus]]
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[[Category: Bahat, Y]]
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[[Category: Bahat Y]]
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[[Category: Dessau, M]]
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[[Category: Dessau M]]
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[[Category: Attachment]]
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[[Category: Envelope protein]]
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[[Category: Receptor binding]]
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[[Category: Viral assembly]]
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[[Category: Viral entry]]
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[[Category: Viral protein]]
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Current revision

Crystal structure of TSWV glycoprotein N ectodomain (Trypsin treated)

PDB ID 6ya2

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