2kji

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Current revision (05:19, 17 October 2024) (edit) (undo)
 
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==A divergent ins protein in c. elegans structurally resemble insulin and activates the human insulin receptor==
==A divergent ins protein in c. elegans structurally resemble insulin and activates the human insulin receptor==
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<StructureSection load='2kji' size='340' side='right'caption='[[2kji]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2kji' size='340' side='right'caption='[[2kji]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2kji]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Caeel Caeel]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KJI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KJI FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2kji]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KJI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KJI FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[4ins|4ins]]</div></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ins-6, ZK84.6 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6239 CAEEL])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kji FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kji OCA], [https://pdbe.org/2kji PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kji RCSB], [https://www.ebi.ac.uk/pdbsum/2kji PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kji ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kji FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kji OCA], [https://pdbe.org/2kji PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kji RCSB], [https://www.ebi.ac.uk/pdbsum/2kji PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kji ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ILB5_CAEEL ILB5_CAEEL]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kj/2kji_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kj/2kji_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Caeel]]
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[[Category: Caenorhabditis elegans]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Bass, J]]
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[[Category: Bass J]]
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[[Category: Hua, Q X]]
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[[Category: Hua QX]]
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[[Category: Jia, W H]]
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[[Category: Jia WH]]
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[[Category: Nakarawa, S H]]
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[[Category: Nakarawa SH]]
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[[Category: Ramos, R R]]
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[[Category: Ramos RR]]
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[[Category: Weiss, M A]]
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[[Category: Weiss MA]]
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[[Category: Wilken, R]]
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[[Category: Wilken R]]
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[[Category: C. elegan]]
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[[Category: Cleavage on pair of basic residue]]
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[[Category: Disulfide bond]]
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[[Category: Folding]]
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[[Category: Hormone]]
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[[Category: Ins-6]]
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[[Category: Insulin like peptide]]
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[[Category: Secreted]]
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Current revision

A divergent ins protein in c. elegans structurally resemble insulin and activates the human insulin receptor

PDB ID 2kji

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