2kop

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Current revision (08:15, 30 October 2024) (edit) (undo)
 
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==NMR solution structures of 3-oxooctanyl-ACP from Streptomyces coelicolor Fatty Acid Synthase==
==NMR solution structures of 3-oxooctanyl-ACP from Streptomyces coelicolor Fatty Acid Synthase==
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<StructureSection load='2kop' size='340' side='right'caption='[[2kop]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2kop' size='340' side='right'caption='[[2kop]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2kop]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"actinomyces_coelicolor"_(muller_1908)_lieske_1921 "actinomyces coelicolor" (muller 1908) lieske 1921]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KOP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KOP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2kop]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_coelicolor Streptomyces coelicolor]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KOP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KOP FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SYO:[(3S)-3-HYDROXY-2,2-DIMETHYL-4-OXO-4-[[3-OXO-3-[2-(3-OXOOCTYLSULFANYL)ETHYLAMINO]PROPYL]AMINO]BUTYL]+DIHYDROGEN+PHOSPHATE'>SYO</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2koo|2koo]], [[2koq|2koq]], [[2kor|2kor]], [[2kos|2kos]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SYO:[(3S)-3-HYDROXY-2,2-DIMETHYL-4-OXO-4-[[3-OXO-3-[2-(3-OXOOCTYLSULFANYL)ETHYLAMINO]PROPYL]AMINO]BUTYL]+DIHYDROGEN+PHOSPHATE'>SYO</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">acpP, SCO2389, SC4A7.17 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1902 "Actinomyces coelicolor" (Muller 1908) Lieske 1921])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kop FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kop OCA], [https://pdbe.org/2kop PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kop RCSB], [https://www.ebi.ac.uk/pdbsum/2kop PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kop ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kop FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kop OCA], [https://pdbe.org/2kop PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kop RCSB], [https://www.ebi.ac.uk/pdbsum/2kop PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kop ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/P72393_STRCH P72393_STRCH]] Carrier of the growing fatty acid chain in fatty acid biosynthesis.[HAMAP-Rule:MF_01217][RuleBase:RU003545]
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[https://www.uniprot.org/uniprot/P72393_STRCH P72393_STRCH] Carrier of the growing fatty acid chain in fatty acid biosynthesis.[HAMAP-Rule:MF_01217][RuleBase:RU003545]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ko/2kop_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ko/2kop_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Arthur, C J]]
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[[Category: Streptomyces coelicolor]]
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[[Category: Crump, M P]]
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[[Category: Arthur CJ]]
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[[Category: Ploskon, E]]
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[[Category: Crump MP]]
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[[Category: Acyl carrier protein]]
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[[Category: Ploskon E]]
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[[Category: Fatty acid biosynthesis]]
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[[Category: Fatty acid synthase]]
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[[Category: Intermediate binding]]
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[[Category: Lipid synthesis]]
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[[Category: Phosphopantetheine]]
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[[Category: Transport protein]]
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Current revision

NMR solution structures of 3-oxooctanyl-ACP from Streptomyces coelicolor Fatty Acid Synthase

PDB ID 2kop

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