2l3t

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==Solution structure of tandem SH2 domain from Spt6==
==Solution structure of tandem SH2 domain from Spt6==
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<StructureSection load='2l3t' size='340' side='right'caption='[[2l3t]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2l3t' size='340' side='right'caption='[[2l3t]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2l3t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L3T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2L3T FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2l3t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L3T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2L3T FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SPT6, CRE2, SSN20, YGR116W, G6169 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2l3t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l3t OCA], [https://pdbe.org/2l3t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2l3t RCSB], [https://www.ebi.ac.uk/pdbsum/2l3t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2l3t ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2l3t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l3t OCA], [https://pdbe.org/2l3t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2l3t RCSB], [https://www.ebi.ac.uk/pdbsum/2l3t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2l3t ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/SPT6_YEAST SPT6_YEAST]] Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression. Essential for viability.<ref>PMID:9450930</ref> <ref>PMID:12934008</ref> <ref>PMID:15531585</ref> <ref>PMID:16455495</ref>
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[https://www.uniprot.org/uniprot/SPT6_YEAST SPT6_YEAST] Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression. Essential for viability.<ref>PMID:9450930</ref> <ref>PMID:12934008</ref> <ref>PMID:15531585</ref> <ref>PMID:16455495</ref>
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 18824]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Liu, J]]
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[[Category: Saccharomyces cerevisiae]]
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[[Category: Shi, Y]]
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[[Category: Liu J]]
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[[Category: Wu, J]]
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[[Category: Shi Y]]
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[[Category: Zhang, J]]
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[[Category: Wu J]]
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[[Category: Sh2]]
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[[Category: Zhang J]]
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[[Category: Spt6]]
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[[Category: Transcription]]
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Revision as of 08:17, 18 January 2023

Solution structure of tandem SH2 domain from Spt6

PDB ID 2l3t

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