2lau
From Proteopedia
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==Solution structure of the THAP-zinc finger domain 1-81 from the cell growth suppressor human THAP11 protein== | ==Solution structure of the THAP-zinc finger domain 1-81 from the cell growth suppressor human THAP11 protein== | ||
| - | <StructureSection load='2lau' size='340' side='right'caption='[[2lau | + | <StructureSection load='2lau' size='340' side='right'caption='[[2lau]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2lau]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2lau]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LAU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LAU FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">THAP11, HRIHFB2206 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lau OCA], [https://pdbe.org/2lau PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lau RCSB], [https://www.ebi.ac.uk/pdbsum/2lau PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lau ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lau OCA], [https://pdbe.org/2lau PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lau RCSB], [https://www.ebi.ac.uk/pdbsum/2lau PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lau ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/THA11_HUMAN THA11_HUMAN] Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers (By similarity). | |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Campagne | + | [[Category: Campagne S]] |
| - | [[Category: Durand | + | [[Category: Durand J]] |
| - | [[Category: Gervais | + | [[Category: Gervais V]] |
| - | [[Category: Milon | + | [[Category: Milon A]] |
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Revision as of 08:29, 18 January 2023
Solution structure of the THAP-zinc finger domain 1-81 from the cell growth suppressor human THAP11 protein
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