1ae5
From Proteopedia
(Difference between revisions)
(New page: 200px<br /> <applet load="1ae5" size="450" color="white" frame="true" align="right" spinBox="true" caption="1ae5, resolution 2.3Å" /> '''HUMAN HEPARIN BINDIN...) |
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| - | [[Image:1ae5.gif|left|200px]]<br /> | + | [[Image:1ae5.gif|left|200px]]<br /><applet load="1ae5" size="350" color="white" frame="true" align="right" spinBox="true" |
| - | <applet load="1ae5" size=" | + | |
caption="1ae5, resolution 2.3Å" /> | caption="1ae5, resolution 2.3Å" /> | ||
'''HUMAN HEPARIN BINDING PROTEIN'''<br /> | '''HUMAN HEPARIN BINDING PROTEIN'''<br /> | ||
==Overview== | ==Overview== | ||
| - | The structure of human heparin binding protein reveals that the serine | + | The structure of human heparin binding protein reveals that the serine proteinase fold has been used as a scaffold for a multifunctional protein with antibacterial activity, monocyte and t-cell activating properties and endotoxin and heparin binding capacity. |
==About this Structure== | ==About this Structure== | ||
| - | 1AE5 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with NAG as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http:// | + | 1AE5 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NAG:'>NAG</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AE5 OCA]. |
==Reference== | ==Reference== | ||
| Line 14: | Line 13: | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| - | [[Category: Bjorn, S | + | [[Category: Bjorn, S E.]] |
| - | [[Category: Flodgaard, H | + | [[Category: Flodgaard, H J.]] |
| - | [[Category: Iversen, L | + | [[Category: Iversen, L F.]] |
| - | [[Category: Kastrup, J | + | [[Category: Kastrup, J S.]] |
| - | [[Category: Larsen, I | + | [[Category: Larsen, I K.]] |
| - | [[Category: Rasmussen, P | + | [[Category: Rasmussen, P B.]] |
| - | [[Category: Wiberg, F | + | [[Category: Wiberg, F C.]] |
[[Category: NAG]] | [[Category: NAG]] | ||
[[Category: antibacterial]] | [[Category: antibacterial]] | ||
| Line 31: | Line 30: | ||
[[Category: serine protease homolog]] | [[Category: serine protease homolog]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 11:43:29 2008'' |
Revision as of 09:43, 21 February 2008
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HUMAN HEPARIN BINDING PROTEIN
Overview
The structure of human heparin binding protein reveals that the serine proteinase fold has been used as a scaffold for a multifunctional protein with antibacterial activity, monocyte and t-cell activating properties and endotoxin and heparin binding capacity.
About this Structure
1AE5 is a Single protein structure of sequence from Homo sapiens with as ligand. Full crystallographic information is available from OCA.
Reference
Structure of HBP, a multifunctional protein with a serine proteinase fold., Iversen LF, Kastrup JS, Bjorn SE, Rasmussen PB, Wiberg FC, Flodgaard HJ, Larsen IK, Nat Struct Biol. 1997 Apr;4(4):265-8. PMID:9095193
Page seeded by OCA on Thu Feb 21 11:43:29 2008
